Russian Cardiologic Scientific and Production Complex, Moscow EUROPEAN RECOMMENDATIONS ON THERAPY OF DYSLIPIDEMIAS – 2016 LIPID-LOWERING THERAPY IN PATIENTS WITH ACUTE CORONARY SYNDROME AND PERCUTANEOUS CORONARY INTERVENTIONS

نویسنده

  • Y. A. KARPOV
چکیده

В структуре смертности нашей страны почти половина от всех фатальных исходов приходится на сердечно-сосудистые заболевания, главным образом на различные формы ишемической болезни (ИБС), включая острый коронарный синдром (ОКС) [1]. Основной причиной ИБС является атеросклероз коронарных артерий, развитие и прогрессирование которого зависит преимущественно от уровня холестерина липопротеидов низкой плотности (ХсЛНП) сыворотки крови, что обусловило целенаправленный поиск и разработку лекарственных препаратов, влияющих на содержание и метаболизм липидов [2]. Среди групп медикаментозных средств, обладающих липидснижающим действием, статины оказались самыми эффективными препаратами, стабильно и значительно снижающими уровень ХсЛНП. В то же время были получены данные о том, что действие статинов выходит за рамки только снижения уровня липидов крови. Было показано, что лечение статинами сопровождается улучшением клинического течения ИБС, уменьшением риска развития фатальных и нефатальных инфарктов миокарда (ИМ), снижением сердечно-сосудистой и общей смертности [3]. Ю.А. КАРПОВ, д.м.н., профессор, О.С. БУЛКИНА, к.м.н. Российский кардиологический научно-производственный комплекс, Москва

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تاریخ انتشار 2016